par Haberle, Sasha Jenkins;Rimoin, Lauren;Trakatelli, Myrto Georgia 
;Zwald, Fiona
Référence High-Risk Cutaneous Squamous Cell Carcinoma: A Practical Guide for Patient Management, Springer Berlin Heidelberg, page (127-148)
Publication Publié, 2016-01
;Zwald, FionaRéférence High-Risk Cutaneous Squamous Cell Carcinoma: A Practical Guide for Patient Management, Springer Berlin Heidelberg, page (127-148)
Publication Publié, 2016-01
Partie d'ouvrage collectif
| Résumé : | Optimal management of patients with one or multiple cutaneous squamous cell carcinomas (cSCC) should take into account both the characteristics of the tumor itself (tumor risk factors) as well as the clinical setting within which the neoplasia arises (patient risk factors). Use of cyclical topical therapy has been added to surgical excision of individual tumors in the treatment of actinic keratosis and in situ cSCC in patients with large regions of sun-damaged skin (field disease), with good success in reducing overall burden of premalignant and early in situ disease. Early evidence suggests that such topical field therapy of actinically damaged skin decreases invasive cSCC formation as well. Follow up of patients with severe actinic damage and/or a history of multiple cSCCs may be performed within the setting of a dedicated high-risk skin cancer dermatology clinic where available to allow for proactive care and close surveillance. Education, prevention, and early intervention are very important tools in the management of patients with field disease and multiple cSCCs. |
