Article révisé par les pairs
Titre:
  • Subversion of mRNA degradation pathways by EWSR1::FLI1 represents a therapeutic vulnerability in Ewing sarcoma.
Auteur:Galvan, Bartimee; Ongena, Loïc; Bruyr, Jonathan; Fettweis, Gregory; Lucarelli, Eva; Lavergne, Arnaud; Mariavelle, Emeline; O'Grady, Tina M; Hassoun, Zahrat El Oula; Claes, Margaux; Dubois, Laurence; Lee, Kevin A W; Kruys, Véronique; Gueydan, Cyril; Durand, Jules; Hervouet, Eric; Geyer, Florian FH; Banito, Ana; Imle, Roland; Mao, Lianghao; Jayavelu, Ashok AK; Grünewald, Thomas TGP; Cidre-Aranaz, Florencia; Twizere, Jean-Claude; Dequiedt, Franck
Informations sur la publication:Nature communications, 16, 1, page (6537)
Statut de publication:Publié, 2025-07-01
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Sarcoma, Ewing -- genetics -- metabolism -- pathology
Humans
Proto-Oncogene Protein c-fli-1 -- metabolism -- genetics
RNA Stability -- genetics
RNA-Binding Protein EWS -- metabolism -- genetics
Cell Line, Tumor
Animals
Oncogene Proteins, Fusion -- metabolism -- genetics
Mice
RNA, Messenger -- metabolism -- genetics
RNA-Binding Proteins -- metabolism -- genetics
Gene Expression Regulation, Neoplastic
Bone Neoplasms -- genetics -- metabolism
Langue:Anglais
Identificateurs:urn:issn:2041-1723
info:doi/10.1038/s41467-025-61725-x
info:pii/10.1038/s41467-025-61725-x
info:pmid/40664627
PMC12263829

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