Article révisé par les pairs
Titre:
  • Continuous replenishment of the dysfunctional CD8 T cell axis is associated with response to chemoimmunotherapy in advanced breast cancer.
Auteur:Metoikidou, Christina; Karnaukhov, Vadim; Boeckx, Bram; Timperi, Eleonora; Bonté, Pierre Emmanuel; Wang, Ling; Espenel, Marion; Albaud, Benoit; Loirat, Delphine; Wang, Xiaoxiao; Sotiriou, Christos; Aftimos, Philippe; Punie, Kevin; Wildiers, Hans; Labroska, Viktorija; Wang, Ming-Wei; Waterfall, Joshua J.J.; Piccart-Gebhart, Martine; Mora, Thierry; Walczak, Aleksandra; Lantz, Olivier; Buisseret, Laurence; Lambrechts, Diether; Amigorena, Sebastian; Romano, Emanuela
Informations sur la publication:Cell Reports Medicine, 6, 3, page (101973)
Statut de publication:Publié, 2025-03
Sujet CREF:Sciences bio-médicales et agricoles
Mots-clés:CD8
T cell clonal dynamics
T cell clonality
T cells
TCR repertoire
anti-CD73
anti-PD(L)1
chemo-immunotherapy
response to chemo-immunotherapy
triple-negative breast cancer
MeSH keywords:Humans
CD8-Positive T-Lymphocytes -- immunology -- drug effects
Female
Triple Negative Breast Neoplasms -- immunology -- drug therapy -- pathology
Immunotherapy -- methods
Middle Aged
Breast Neoplasms -- immunology -- drug therapy -- pathology
Single-Cell Analysis
Immune Checkpoint Inhibitors -- therapeutic use
Aged
Langue:Anglais
Identificateurs:urn:issn:2666-3791
info:doi/10.1016/j.xcrm.2025.101973
info:pii/S2666-3791(25)00046-1
info:pmid/39983715
PMC11970331

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