par Li, Man;Jafari, Hafez 
;Okoro, Oseweuba ;Nie, Lei ;Shavandi, Armin
Référence Colloids and surfaces. A, Physicochemical and engineering aspects, 710, page (136109)
Publication Publié, 2025-04-01
;Okoro, Oseweuba ;Nie, Lei ;Shavandi, Armin Référence Colloids and surfaces. A, Physicochemical and engineering aspects, 710, page (136109)
Publication Publié, 2025-04-01
Article révisé par les pairs
| Résumé : | Metal-phenolic networks (MPNs) have drawn widespread attention due to their facile synthesis process, favorable biocompatibility, and antimicrobial properties. The present study investigated an environmentally friendly method for synthesizing manganese-tannic acid (Mn-TA) complexes with peroxidase (POD) like properties. The research focuses on optimizing the yield and enzyme-mimetic activity of the Mn-TA complex. A ligand-to-metal charge transfer band at approximately 603 cm⁻¹ in the FTIR spectrum suggested that Mn-TA complexes had been successfully formed. The Box-Behnken Design (BBD) was employed to evaluate the influence of key variables, including pH (4–10), temperature (25–90 °C), the molar ratio of Mn2 + to TA (1:1–1:6), and reaction time (1–6 h), on the yield and enzyme-mimetic activity. Enzyme-mimetic activity was quantified using absorbance spectroscopy. The optimum yield and absorbance of the Mn-TA complex of 72.88 wt% and 0.694 AU, respectively, were achieved at the conditions of pH 10.0, temperature 43 °C, molar ratio of 1:1, and a reaction time of 6 h. The optimally produced Mn-TA complexes displayed a POD-like activity with an estimated Michaelis-Menten constant value of 0.481 mM. The study also showed Mn-TA complexes possess biocompatibility and have antibacterial activities. |
