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Pre-OPerative accelerated radiotherapy for early stage breast cancer patients (POPART): A feasibility study

par Mulliez, Thomas;Miedema, Geertje;Van Parijs, Hilde;Hottat, Nathalie ;Vassilieff, Maud ;Gillet, Evy;Baeyens, Luc ;Voordeckers, Mia;Coelmont, Jolien;Besse-Hammer, Tatiana;Gevaert, Thierry;Nazac, Andre ;De Ridder, Mark
Référence Radiotherapy and oncology, 170, page (118-121)
Publication Publié, 2022-05

Article révisé par les pairs

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Résumé :

Pre-operative 5-fraction breast radiotherapy followed by immediate breast-sparing surgery and sentinel node procedure was feasible in 14 patients with 15 clinical early-stage breast cancers. However wound problems occurred frequently and was documented in 5 of the 14 patients: 2 patients with a mastitis needing antibiotics, 2 patients developed a fistula with exudate needing antibiotics and local disinfection and 1 patient developed a fistula needing surgical reintervention. Other acute and late iatrogenic events were rather limited. Two patients had a pathological lymph node involvement, which underlines the importance to perform the sentinel node procedure before pre-operative radiotherapy.