par Diamante Chiodini, Benedetta;Ismaili, Khalid ;Diamond, David D.A.;Kurtz, Michael M.P.
Référence Pediatric Kidney Disease, Springer International Publishing, page (1211-1220)
Publication Publié, 2023-01
Partie d'ouvrage collectif
Résumé : Obstructive uropathy is the partial or complete blockage of the flow of urine, which can occur as the consequence of an anomaly at any level of the urinary system: the ureteropelvic junction, distal ureter or ureterocele, urethra or extrinsic compression by other structures (e.g., blood vessels, tumors). As most of these conditions are congenital, they are currently routinely diagnosed before birth in developed countries. Pyelectasis and hydronephrosis are the most common signs of obstruction detected on ultrasound, although they are not the only ones. Obstructive uropathy is the most common cause of end-stage renal disease in children, and the clinical management is still a challenge for nephrologists and urologists. This is due to the wide spectrum of severity and clinical progression, the difficulty predicting long-term prognosis and sometimes the inability to reverse renal damage. This chapter outlines the imaging and clinical features as well as current treatment options of the most common obstructive uropathies, such as ureteropelvic junction obstruction, ureterovesical junction obstruction, complicated renal duplications and posterior urethral valves. A pragmatic clinical approach is also proposed for each pathology.