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Variability of cortico-cortical evoked potentials in the epileptogenic zone is related to seizure occurrence.

par Feys, Odile ;Wens, Vincent ;Schuind, Sophie ;Rikir, Estelle ;Legros, Benjamin ;De Tiege, Xavier ;Gaspard, Nicolas
Référence Annals of clinical and translational neurology, 11, 10, page (2645-2656)
Publication Publié, 2024-10

Article révisé par les pairs

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Résumé :

Cortico-cortical evoked potentials (CCEPs) were described as reproducible during trains of single-pulse electrical stimulations (SPES). Still, few studies described a variability of CCEPs that was higher within the epileptogenic zone (EZ). This study aimed at characterizing the relationship of CCEP variability with the occurrence of interictal/ictal epileptiform discharges at the temporal vicinity of the stimulation, but not during the stimulation, by effective connectivity modifications.