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Haemodynamic validation of the three-step HFA-PEFF algorithm to diagnose heart failure with preserved ejection fraction.

par Lanzarone, Ettore;Baratto, Claudia;Vicenzi, Marco ;Villella, Francesco;Rota, Irene;Dewachter, Céline ;Muraru, Denisa;Tomaselli, Michele;Gavazzoni, Mara;Badano, Luigi P;Senni, Michele;Vachiéry, Jean-Luc;Parati, Gianfranco;Caravita, Sergio
Référence ESC Heart Failure, 10, 4, page (2588-2595)
Publication Publié, 2023-08-01

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Résumé :

The HFA-PEFF algorithm (Heart Failure Association-Pre-test assessment, Echocardiography and natriuretic peptide score, Functional testing in cases of uncertainty, Final aetiology) is a three-step algorithm to diagnose heart failure with preserved ejection fraction (HFpEF). It provides a three-level likelihood of HFpEF: low (score < 2), intermediate (score 2-4), or high (score > 4). HFpEF may be confirmed in individuals with a score > 4 (rule-in approach). The second step of the algorithm is based on echocardiographic features and natriuretic peptide levels. The third step implements diastolic stress echocardiography (DSE) for controversial diagnostic cases. We sought to validate the three-step HFA-PEFF algorithm against a haemodynamic diagnosis of HFpEF based on rest and exercise right heart catheterization (RHC).