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Lung diffusion capacity correlates with pre-implant pulmonary hypertension and predicts outcome after LVAD implantation.

par Macera, Francesca ;Dewachter, Céline ;Stefanidis, Constantin ;Vanden Eynden, Frédéric ;Bondue, Antoine ;Vachiery, Jean-Luc ;Roussoulieres, Ana
Référence ESC Heart Failure, 10, 2, page (1043-1053)
Publication Publié, 2023-04

Article révisé par les pairs

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Résumé :

Diffusing capacity of the lung for carbon monoxide (DLCO ) reduction is common in heart failure (HF) and is associated with a worse prognosis. Correlations between DLCO and pulmonary hypertension (PH) are unclear, and published data are conflicting; it has been shown that DLCO impairment may persist or even worsen after normalization of pulmonary pressures following left ventricle assist device (LVAD) implantation, maybe reflecting persistent pulmonary damage. We aimed to investigate the impact of pre-implant DLCO and central haemodynamics on outcome in patients with advanced HF implanted with a LVAD.