Effect of screening for Neisseria gonorrhoeae and Chlamydia trachomatis on incidence of these infections in men who have sex with men and transgender women taking HIV pre-exposure prophylaxis (the Gonoscreen study): results from a randomised, multicentre, controlled trial.

Vanbaelen, Thibaut; Tsoumanis, Achilleas; Florence, Eric; Van Dijck, Christophe; Huis In 't Veld, Diana; Sauvage, Anne Sophie; Herssens, Natacha; De Baetselier, Irith; Rotsaert, Anke; Verhoeven, Veronique; Henrard, Sophie; Van Herrewege, Yven; Van den Bossche, Dorien; Goffard, Jean-Christophe; Padalko, Elizaveta; Reyniers, Thijs; Vuylsteke, Bea; Hayette, Marie-Pierre; Libois, Agnès; Kenyon, Christopher

doi:doi/10.1016/S2352-3018(23)00299-0

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Résumé :

Guidelines recommend screening for Neisseria gonorrhoeae and Chlamydia trachomatis at three anatomical sites (urethra, anus, and pharynx) every 3 months (3 × 3) in men who have sex with men (MSM) and transgender women taking HIV pre-exposure prophylaxis (PrEP). We present the first randomised controlled trial to compare the effect of screening versus non-screening for N gonorrhoeae and C trachomatis on the incidence of these infections in MSM and transgender women taking PrEP.

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