Titre:
  • Bax Inhibitor-1 preserves pancreatic β-cell proteostasis by limiting proinsulin misfolding and programmed cell death.
Auteur:Blanc, Marina; Habbouche, Lama; Xiao, Peng; Lebeaupin, Cynthia; Janona, Marion; Vaillant, Nathalie; Irondelle, Marie; Gilleron, Jérôme; Murcy, Florent; Rousseau, Déborah; Luci, Carmelo; Barouillet, Thibault; Marchetti, Sandrine; Lacas-Gervais, Sandra; Yvan-Charvet, Laurent; Gual, Philippe; Cardozo, Alessandra K; Bailly Maître, Beatrice
Informations sur la publication:Cell death & disease, 15, 5, page (334)
Statut de publication:Publié, 2024-05-01
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Animals
Insulin-Secreting Cells -- metabolism -- pathology
Proinsulin -- metabolism
Mice
Endoplasmic Reticulum Stress
Apoptosis
Unfolded Protein Response
Proteostasis
Membrane Proteins -- metabolism -- genetics
Protein Folding
Endoribonucleases -- metabolism
Mice, Inbred C57BL
Diet, High-Fat
Mice, Knockout
Male
Note générale:SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:E230326
info:doi/10.1038/s41419-024-06701-x
info:pii/10.1038/s41419-024-06701-x
info:scp/85193011133
info:pmid/38744890
PMC11094198