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Cluster-mediated stop-and-go crystallization‬

par Van Driessche, Alexander E.S.;Lutsko, James ;Maes, Dominique;Sleutel, Mike
Référence Journal of crystal growth, 603, 127024
Publication Publié, 2023-02

Article révisé par les pairs

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Résumé :

Impurities control the formation of bio-crystals and can fully paralyze crystal growth at low levels of supersaturation. Traditional impurity models predict that an escape from this so-called “dead zone” requires an increase in the driving force (i.e. supersaturation). In this work, using protein crystals as a model system, we uncover an alternative escape route from the dead zone that does not involve an increase in supersaturation. We demonstrate that the merger of a protein cluster with the crystal surface triggers the formation of an ordered multi-layered island. The newly created surface on top of the resulting 3D island is initially devoid of impurities and therefore characterized by near-pure step growth kinetics. The accelerated step advancement on this relatively uncontaminated surface limits the available time for impurities to adsorb on the emerging terraces and by extension their resulting surface density. Cluster-mediated crystal growth occurring in heterogeneous media can therefore lead to stop-and-go dynamics, which offers a new model to explain crystallization taking place under biological control (e.g. biomineralization).