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Impact of the C1431T Polymorphism of the Peroxisome Proliferator Activated Receptor-Gamma (PPAR-γ) Gene on Fasted Serum Lipid Levels in Patients with Coronary Artery Disease.

par Oladi, Mohammadreza;Nohtani, Mahdi;Avan, Amir;Mirhafez, Seyed Reza;Tajbakhsh, Amir;Ghasemi, Faezeh;Asadi, Asadollah;Elahdadi Salmani, Mahmoud;Mohammadi, Akram;Hosseinzadeh, Leila ;Ferns, Gordon A;Ghayour Mobarhan, Majid
Référence Annals of nutrition & metabolism, 66, 2-3, page (149-154)
Publication Publié, 2015

Article révisé par les pairs

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Résumé :

The C1431T polymorphism of peroxisome proliferator activated receptor-γ (PPAR-γ) gene is related to diabetes and metabolic-syndrome. However, studies have been inconclusive about its association with coronary artery disease (CAD) and there have been no studies analyzing the association of this polymorphism with fasted-serum-lipid levels in Iranian-individuals with CAD. We investigated the association of PPAR-γ C1431T-polymorphism with CAD and dyslipidaemia in 787 individuals.