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Hypotension-Avoidance Versus Hypertension-Avoidance Strategies in Noncardiac Surgery : An International Randomized Controlled Trial.

par Marcucci, Maura;Painter, Thomas TW;Conen, David;Lomivorotov, Vladimir;Sessler, Daniel I;Chan, Matthew T V;Borges, Flavia K;Leslie, Kate;Duceppe, Emmanuelle;Martínez-Zapata, María José;Wang, Chew Yin;Xavier, Denis;Ofori, Sandra N;Wang, Michael Ke;Efremov, Sergey;Landoni, Giovanni;Kleinlugtenbelt, Ydo YV;Szczeklik, Wojciech;Schmartz, Denis ;Garg, Amit X;Short, Timothy TG;Wittmann, Maria;Meyhoff, Christian Sylvest;Amir, Mohammed;Torres, David ;Patel, Ameen;Ruetzler, Kurt;Parlow, Joel JL;Tandon, Vikas;Fleischmann, Edith;Polanczyk, Carísi Anne;Lamy, Andre;Jayaram, Raja;Astrakov, Sergey SV;Wu, William Ka Kei;Cheong, Chao Chia;Ayad, Sabry;Kirov, Mikhail M.Y.;de Nadal, Miriam;Likhvantsev, Valery VV;Paniagua, Pilar;Aguado, Hector HJ;Maheshwari, Kamal;Whitlock, Richard RP;McGillion, Michael MH;Vincent, Jessica;Copland, Ingrid;Balasubramanian, Kumar;Biccard, Bruce BM;Srinathan, Sadeesh;Ismoilov, Samandar;Pettit, Shirley;Stillo, David;Kurz, Andrea;Belley-Côté, Emilie EP;Spence, Jessica;McIntyre, William WF;Bangdiwala, Shrikant SI;Guyatt, Gordon;Yusuf, Salim;Devereaux, P J;POISE-3 Trial Investigators and Study Groups,
Référence Annals of internal medicine, 176, 5, page (605-614)
Publication Publié, 2023-05-01

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Résumé :

Among patients having noncardiac surgery, perioperative hemodynamic abnormalities are associated with vascular complications. Uncertainty remains about what intraoperative blood pressure to target and how to manage long-term antihypertensive medications perioperatively.