Article révisé par les pairs
Titre:
  • Pharmacological targeting of netrin-1 inhibits EMT in cancer.
Auteur:Lengrand, Justine; Pastushenko, Ievgenia; Vanuytven, Sebastiaan; Song, Yura; Venet, David; Sarate, Rahul Maruti; Bellina, Melanie; Moers, Virginie; Boinet, Alice; Sifrim, Alejandro; Rama, Nicolas; Ducarouge, Benjamin; Van Herck, Jens; Dubois, Christine; Scozzaro, Samuel; Lemaire, Sophie; Gieskes, Sarah; Bonni, Sophie; Collin, Amandine; Braissand, Nicolas; Allard, Justine; Zindy, Egor; Decaestecker, Christine; Sotiriou, Christos; Salmon, Isabelle; Mehlen, Patrick; Voet, Thierry; Bernet, Agnès; Blanpain, Cédric
Informations sur la publication:Nature (London)
Statut de publication:Publié, 2023-08-01
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Animals
Humans
Mice
A549 Cells
Carcinoma, Squamous Cell -- drug therapy -- pathology
Cell Line, Tumor
Epithelial-Mesenchymal Transition -- drug effects
Netrin Receptors -- antagonists & inhibitors -- deficiency -- genetics
Netrin-1 -- antagonists & inhibitors -- deficiency -- genetics
RNA, Small Interfering -- genetics -- pharmacology
Disease Models, Animal
Skin Neoplasms -- drug therapy -- pathology
Antibodies, Monoclonal -- pharmacology -- therapeutic use
Neoplasm Metastasis -- drug therapy
Single-Cell Gene Expression Analysis
RNA-Seq
Epithelial Cell Adhesion Molecule -- metabolism
Xenograft Model Antitumor Assays
Transforming Growth Factor beta1 -- pharmacology
Note générale:SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:0028-0836
info:doi/10.1038/s41586-023-06372-2
info:pii/10.1038/s41586-023-06372-2
info:scp/85166544703
info:pmid/37532929
PMC7615210

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