Titre:
  • A selective inhibitor of the sperm-specific potassium channel SLO3 impairs human sperm function.
Auteur:Lyon, Maximilian; Li, Ping; Ferreira, Juan José́; Lazarenko, Roman RM; Kharade, Sujay SV; Kramer, Meghan; McClenahan, Samantha SJ; Days, Emily; Bauer, Joshua A; Spitznagel, Brittany BD; Weaver, C David; Borrego Alvarez, Aluet; Puga Molina, Lis C; Lybaert, Pascale; Khambekar, Saayli; Liu, Alicia; Lindsley, Craig CW; Denton, Jerod; Santi, Celia Maria
Informations sur la publication:Proceedings of the National Academy of Sciences of the United States of America, 120, 4, page (e2212338120)
Statut de publication:Publié, 2023-01
Sujet CREF:Sciences bio-médicales et agricoles
Mots-clés:SLO3
capacitation
drug discovery
human sperm
ion channels
MeSH keywords:Humans
Male
Infertility, Male
Large-Conductance Calcium-Activated Potassium Channels -- antagonists & inhibitors
Membrane Potentials -- physiology
Semen
Spermatozoa -- physiology
Note générale:SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:0027-8424
info:doi/10.1073/pnas.2212338120
info:scp/85146403939
info:pmid/36649421
PMC9942793