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Group 2 Pulmonary Hypertension: Clinical Features and Treatment

par Vachiery, Jean-Luc ;Caravita, Sergio
Référence Encyclopedia of Respiratory Medicine, Second Edition, Elsevier, Vol. 3, page (665-677)
Publication Publié, 2021-01

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Résumé :

Pulmonary hypertension (PH) is frequent in left heart disease (LHD), especially in heart failure with preserved ejection fraction (HFpEF). In contrast with group 1 PH, PH due to HFpEF is triggered by the underlying condition through a passive increase in left atrial pressure. A small subset of patients may present pulmonary vascular disease, which has a greater impact on exercise capacity, outcome and represents a diagnostic challenge. This chapter highlights the importance of properly phenotyping group 2 PH patients and the lack of evidence supporting the use of specific therapies for this condition.