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Global profiling of genes modified by endoplasmic reticulum stress in pancreatic beta cells reveals the early degradation of insulin mRNAs

par Pirot, Pierre ;Naamane, Najib ;Libert, Frédérick ;Magnusson, N. E.;Orntoft, Torben Falck;Cardozo, Alessandra K ;Eizirik, Decio L.
Référence Diabetologia, page (1229-1236)
Publication Publié, 2007

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Titre:	Global profiling of genes modified by endoplasmic reticulum stress in pancreatic beta cells reveals the early degradation of insulin mRNAs
Auteur:	Pirot, Pierre; Naamane, Najib; Libert, Frédérick; Magnusson, N. E.; Orntoft, Torben Falck; Cardozo, Alessandra K; Eizirik, Decio L.
Informations sur la publication:	Diabetologia, page (1229-1236)
Statut de publication:	Publié, 2007
Sujet CREF:	Médecine clinique [biologie clinique]
Mots-clés:	Apoptosis
	CPA
	Cyclopiazonic acid
	Diabetes mellitus
	Endoplasmic reticulum stress
	Insulin
	Interleukin-1
	Pancreatic beta cells
MeSH keywords:	Cell Line
	Cell Survival
	Cells, Cultured
	Endoplasmic Reticulum -- physiology
	Gene Expression Profiling
	Gene Expression Regulation
	Humans
	Indoles -- pharmacology
	Insulin -- genetics
	Insulin-Secreting Cells -- cytology
	Insulin-Secreting Cells -- drug effects
	Insulin-Secreting Cells -- physiology
	Kinetics
	Oligonucleotide Array Sequence Analysis
	Polymerase Chain Reaction
	RNA, Messenger -- metabolism
	Stress, Mechanical
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0012-186X
	info:doi/10.1007/s00125-007-0609-0
	info:scp/34147106529
	info:pmid/17333111
	ppi-0005