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Interferon-gamma potentiates endoplasmic reticulum stress-induced death by reducing pancreatic beta cell defence mechanisms

par Pirot, Pierre ;Eizirik, Decio L. ;Cardozo, Alessandra K
Référence Diabetologia, 49, page (1229-1236)
Publication Publié, 2006

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Titre:	Interferon-gamma potentiates endoplasmic reticulum stress-induced death by reducing pancreatic beta cell defence mechanisms
Auteur:	Pirot, Pierre; Eizirik, Decio L.; Cardozo, Alessandra K
Informations sur la publication:	Diabetologia, 49, page (1229-1236)
Statut de publication:	Publié, 2006
Sujet CREF:	Médecine clinique [biologie clinique]
Mots-clés:	Apoptosis
	Endoplasmic reticulum stress
	Interferon-γ
	Pancreatic beta cells
	Type 1 diabetes mellitus
MeSH keywords:	Animals
	Apoptosis -- drug effects
	Calcium -- metabolism
	Cell Death -- drug effects
	Cell Line
	Cell Survival -- drug effects
	Endoplasmic Reticulum -- drug effects
	Endoplasmic Reticulum -- physiology
	Endoplasmic Reticulum -- ultrastructure
	Gene Expression Regulation -- drug effects
	Gene Expression Regulation -- physiology
	Indoles -- pharmacology
	Insulin-Secreting Cells -- drug effects
	Insulin-Secreting Cells -- physiology
	Interferon-gamma -- pharmacology
	Interleukin-1 -- pharmacology
	Rats
	Reverse Transcriptase Polymerase Chain Reaction
	Stress, Mechanical
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0012-186X
	info:doi/10.1007/s00125-006-0214-7
	info:scp/33646533330
	info:pmid/16604358
	ppi-0003