par Jacob, Clément 
;Annibaletto, Julien ;Maes, Bert U. W.;Evano, Gwilherm
Référence Synthesis, 55, page (1799-1823)
Publication Publié, 2023-02-21
;Annibaletto, Julien ;Maes, Bert U. W.;Evano, Gwilherm Référence Synthesis, 55, page (1799-1823)
Publication Publié, 2023-02-21
Article révisé par les pairs
| Résumé : | Anilines selectively arylated at their ortho-, meta- or para- positions are useful building blocks in synthesis and have found applications in many areas. The most straightforward method for their synthesis relies on the direct arylation of a C(sp2)-H bond of anilines, an attractive strategy avoiding the prefunctionalization of the starting anilines provided that such arylations proceed with high levels of regioselectivity. Such reactions are presented and discussed, in a comprehensive manner, in this review article, with an emphasis on the regioselectivity of the processes and factors governing both the reactivity and selectivity. |
