Résumé : Abstract. With more than 15 years of continuous and consistent measurements, the Infrared Atmospheric Sounding Interferometer (IASI) radiance dataset is becoming a reference climate data record. To be exploited to its full potential, it requires a cloud filter that is accurate, unbiased over the full IASI life span and strict enough to be used in satellite data retrieval schemes.Here, we present a new cloud detection algorithm which combines (1) a high sensitivity, (2) a good consistency over the whole IASI time series and between the different copies of the instrument flying on board the suite of Metop satellites, and (3) simplicity in its parametrization.The method is based on a supervised neural network (NN) and relies, as input parameters, on the IASI radiance measurements only. The robustness of the cloud mask over time is ensured in particular by avoiding the IASI channels that are influenced by CO2, N2O, CH4, CFC-11 and CFC-12 absorption lines and those corresponding to the ν2 H2O absorption band. As a reference dataset for the training, version 6.5 of the operational IASI Level 2 (L2) cloud product is used.We provide different illustrations of the NN cloud product, including comparisons with other existing products. We find very good agreement overall with version 6.5 of the operational IASI L2 with an identical mean annual cloud amount and a pixel-by-pixel correspondence of about 87 %. The comparison with the other cloud products shows a good correspondence in the main cloud regimes but with sometimes large differences in the mean cloud amount (up to 10 %) due to the specificities of each of the different products.We also show the good capability of the NN product to differentiate clouds from dust plumes.