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Effects of the flow diversion technique on nucleotide levels in intra-cranial aneurysms: A feasibility study providing new research perspectives.

par Eker, Omer Faruk;Lubicz, Boris ;Cortese, Melissa ;Delporte, Cédric ;Berhouma, Moncef;Chopard, Bastien;Costalat, Vincent;Bonafé, Alain;Alix-Panabières, Catherine;Van Antwerpen, Pierre ;Zouaoui Boudjeltia, Karim
Référence Frontiers in Cardiovascular Medicine, 9, page (885426)
Publication Publié, 2022

Article révisé par les pairs

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Résumé :

The flow diverter stent (FDS) has become a first-line treatment for numerous intra-cranial aneurysms (IAs) by promoting aneurysm thrombosis. However, the biological phenomena underlying its efficacy remain unknown. We proposed a method to collect in situ blood samples to explore the flow diversion effect within the aneurysm sac. In this feasibility study, we assessed the plasma levels of nucleotides within the aneurysm sac before and after flow diversion treatment.