Titre:
  • The small-molecule SMARt751 reverses Mycobacterium tuberculosis resistance to ethionamide in acute and chronic mouse models of tuberculosis.
Auteur:Flipo, Marion; Frita, Rosangela; Bourotte, Marilyne; Martínez-Martínez, María S; Boesche, Markus; Boyle, Gary W; Derimanov, Geo; Drewes, Gerard; Gamallo, Pablo; Ghidelli-Disse, Sonja; Gresham, Stephanie; Jiménez, Elena; de Mercado, Jaime; Pérez-Herrán, Esther; Porras-De Francisco, Esther; Rullas, Joaquín; Casado, Patricia; Leroux, Florence; Piveteau, Catherine; Kiass, Mehdi; Mathys, Vanessa; Soetaert, Karine; Megalizzi, Véronique; Tanina, ABDALKARIM; Wintjens, René; Antoine, Rudy; Brodin, Priscille; Delorme, Vincent; Moune, Martin; Djaout, Kamel; Slupek, Stéphanie; Kemmer, Christian; Gitzinger, Marc; Ballell, Lluis; Mendoza-Losana, Alfonso; Lociuro, Sergio; Déprez, Benoit; Barros-Aguirre, David; Remuiñán, Modesto MJ; Willand, Nicolas; Baulard, Alain R
Informations sur la publication:Science Translational Medicine, 14, 643, page (eaaz6280)
Statut de publication:Publié, 2022-09-01
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Animals
Antitubercular Agents -- pharmacology -- therapeutic use
Ethionamide -- chemistry -- pharmacology -- therapeutic use
Mice
Mycobacterium tuberculosis
Prodrugs -- pharmacology -- therapeutic use
Tuberculosis -- drug therapy
Note générale:SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:1946-6234
info:doi/10.1126/scitranslmed.aaz6280
info:scp/85129346117
info:pmid/35507672