Résumé : Fused Filament Fabrication (FFF) is an extrusion-based Additive Manufacturing method widely used in various industries for prototyping applications. Since FFF's invention in the 1980s, this technology has undergone numerous advancements in terms of available material, software and equipment. Nevertheless, FFF parts are often limited to non-critical, non-load-bearing applications, partly because the existing design and manufacturing tools do not capitalize on FFF's high design freedom. In particular, the slicing software that generates printing instructions prints filaments in predefined patterns and cannot realize filament paths that are locally optimized to enhance the structural performance, thus, hindering the best utilization of FFF parts for load-bearing purposes. The current thesis aims to develop dedicated tools for designing and printing optimized filament paths for improved structural performance from FFF parts. First, an algorithmic framework that optimizes the in-plane filament paths for minimum compliance of FFF structures is presented, particularly focusing on obtaining production-ready design solutions by including the manufacturing constraints in the optimization process. Then, a new filament deposition algorithm is proposed to address the manufacturability issues observed in existing optimization strategies. The proposed algorithm accepts the point-wise orientation fields resulting from the optimization procedures and deploy filaments along the orientation fields to realize optimized designs. Both the contributions facilitate the seamless production of structural FFF parts, which we prove by applying them to design structurally-informed filament trajectories and printing the parts.