par Verset, Laurine ;Huberty, Vincent ;Bourgeois, V.;Lemmers, Arnaud ;Demetter, Pieter
Référence Acta Gastro-Enterologica Belgica (English ed.), 85, 2, page (396-399)
Publication Publié, 2022-04-01
Article révisé par les pairs
Résumé : Background: Esophageal immature squamous metaplasia is hardly reported in the literature. This entity can, however, be misinterpreted as high grade dysplasia or invasive squamous cell carcinoma and hence represent a potential pitfall. Case presentation: Histopathological examination of a superficial esophageal lesion removed by endoscopic submucosal dissection revealed a squamous cell carcinoma associated with immature squamous cell metaplasia arising from esophageal glands. Immunohistochemical stainings allowed to distinguish malignant from metaplastic cells. Conclusions: Immunohistochemistry for Ber-EP4 is helpful in making the distinction between esophageal squamous cell carcinoma and immature squamous metaplasia. This can avoid overstaging and overtreatment, especially in early esophageal cancer. (Acta gastroenterol. belg., 2022, 85, 396-399).