par Belcour, Morgane 
;Dontaine, Pauline ;Monier, Anne ;Lebrun, Laetitia ;Salmon, Isabelle ;De Witte, Olivier ;Goldman, Serge ;De Tiege, Xavier ;Aeby, Alec
Référence Frontiers in Pediatrics, 10, 794294
Publication Publié, 2022-03
;Dontaine, Pauline ;Monier, Anne ;Lebrun, Laetitia ;Salmon, Isabelle ;De Witte, Olivier ;Goldman, Serge ;De Tiege, Xavier ;Aeby, Alec Référence Frontiers in Pediatrics, 10, 794294
Publication Publié, 2022-03
Article révisé par les pairs
| Résumé : | Primary angiitis of the central nervous system (PACNS) is a rare inflammatory disease affecting central nervous system vessels. The diagnosis, which requires confirmation by brain biopsy, remains challenging due to unspecific clinical presentation and low specificity of imaging and laboratory exams. In these two pediatric biopsy-proven cases of svPACNS we demonstrate that brain positron emission tomography (PET) show a high metabolic activity that extends beyond brain MRI abnormalities. Therefore, combining MRI and PET abnormalities to adequately guide brain biopsy might increase the diagnostic yield of this rare condition. |
