Low-Dose Nivolumab with or without Ipilimumab as Adjuvant Therapy Following the Resection of Melanoma Metastases: A Sequential Dual Cohort Phase II Clinical Trial.

Schwarze, Julia Katharina; Garaud, Soizic; Jansen, Yanina J L; Awada, Gil; Vandersleyen, Valerie; Tijtgat, Jens; de Wind, Alexandre; Kristanto, Paulus; Seremet, Teofila T.C.; Willard-Gallo, Karen; Neyns, Bart

doi:doi/10.3390/cancers14030682

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Low-Dose Nivolumab with or without Ipilimumab as Adjuvant Therapy Following the Resection of Melanoma Metastases: A Sequential Dual Cohort Phase II Clinical Trial.

par Schwarze, Julia Katharina ;Garaud, Soizic

;Jansen, Yanina J L ;Awada, Gil ;Vandersleyen, Valerie ;Tijtgat, Jens ;de Wind, Alexandre ;Kristanto, Paulus ;Seremet, Teofila T.C.;Willard-Gallo, Karen ;Neyns, Bart
Référence Cancers (Basel), 14, 3
Publication Publié, 2022-01-01

Article révisé par les pairs

Résumé :

Optimal dosing and duration of adjuvant treatment with PD-1 and CTLA-4 immune checkpoint inhibitors have not been established. Prior to their regulatory approval we investigated a low-dose regimen of nivolumab with or without ipilimumab in a sequential dual-cohort phase II clinical trial.

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