Article révisé par les pairs
Titre:
  • Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis
Auteur:Pastushenko, Ievgenia; Mauri, Federico; Song, Yura; De Cock, Frédérique; Meeusen, Bob; Swedlund, Benjamin; Impens, Francis; Van Haver, Delphi; Opitz, Matthieu; Thery, Manuel; Bareche, Yacine; Lapouge, Gaëlle; Vermeersch, Marjorie; Van Eycke, Yves-Remi; Balsat, Cédric; Decaestecker, Christine; Sokolow, Youri; Hassid, Sergio; Perez-Bustillo, Alicia; Agreda-Moreno, Beatriz; Rios-Buceta, Luis; Jaen, Pedro; Redondo, Pedro; Sieira-Gil, Ramon; Millan-Cayetano, José Francisco; Sanmatrtin, Onofre; D'Haene, Nicky; Moers, Virginie; Rozzi, Milena; Blondeau, Jérémy; Lemaire, Sophie; Scozzaro, Samuel; Janssens, Veerle; De Troya, Magdalena; Dubois, Christine; Perez-Morga, David; Salmon, Isabelle; Sotiriou, Christos; Helmbacher, Françoise; Blanpain, Cédric
Informations sur la publication:Nature (London), 589, 7842, page (448-455)
Statut de publication:Publié, 2021-01-01
Sujet CREF:Sciences biomédicales
MeSH keywords:Adaptor Proteins, Signal Transducing -- metabolism
Animals
Cadherins -- deficiency -- genetics -- metabolism
Carcinoma, Squamous Cell -- genetics -- pathology
Disease Progression
Enhancer of Zeste Homolog 2 Protein -- metabolism
Epithelial Cells -- metabolism -- pathology
Epithelial-Mesenchymal Transition -- drug effects -- genetics
Gene Deletion
Gene Expression Regulation, Neoplastic
Humans
Hyaluronan Receptors -- metabolism
Lung Neoplasms -- genetics -- pathology
Mesoderm -- metabolism -- pathology
Mice
Neoplasm Metastasis -- drug therapy -- genetics
Neoplasms -- drug therapy -- genetics -- pathology
Neoplastic Stem Cells -- metabolism -- pathology
Phenotype
Phosphoproteins -- analysis -- metabolism
Proteomics
SOXB1 Transcription Factors -- metabolism
Signal Transduction
Skin Neoplasms -- genetics -- pathology
Transcription Factors -- metabolism
YAP-Signaling Proteins
Zinc Finger E-box-Binding Homeobox 1 -- metabolism
src-Family Kinases -- metabolism
Note générale:SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:0028-0836
info:doi/10.1038/s41586-020-03046-1
info:pii/3046
info:scp/85097603958
info:pmid/33328637
PMC7612440

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