par Lorenz, Natalie;Ho, Timothy T.K.C.;McGregor, Reuben;Davies, Mark R;Williamson, Deborah D.A.;Gurney, Jason J.K.;Smeesters, Pierre ;Baker, Michael M.G.;Moreland, N.J.
Référence Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 73, 12, page (2322-2325)
Publication Publié, 2021-12
Article révisé par les pairs
Résumé : Rheumatic fever is a serious post-infectious sequela of group A Streptococcus (GAS). Prior GAS exposures were mapped in sera using a large panel of M-type specific peptides. Rheumatic fever patients had serological evidence of significantly more GAS exposures than matched controls suggesting immune priming by repeat infections contributes to pathogenesis.