Résumé : This work was supported by non-profit organizations and public bodies for funding of scientific research conducted within the European Union: the Innovative Medicines Initiative 2 Joint Undertaking, RHAPSODY [115881 to EB, LM, CdL, MS, MT, MI, DLE, MC, PM], INNODIA [115797 to LM, DLE, MC, PM] and INNODIA HARVEST [945268 to LM, DLE,MC, PM] - this Joint Undertaking receives support from the Union's Horizon 2020 research and innovation programme, 'EFPIA', 'JDRF' and 'The Leona M. and Harry B. Helmsley Charitable Trust"(INNODIA, INNODIA HARVEST), the 'EFPIA' and the Swiss State Secretariat for Education, Research and Innovation under contract number 16.0097 (RHAPSODY); the European Union's Horizon 2020 research and innovation programme, project T2DSystems [667191 to EB, LM, CdL,MS,MT, DLE,MC, PM]; theWalloon Region through the FRFS-WELBIO Fund for Strategic Fundamental Research [grant numbers CR-2015A-06s, CR-2019C-04 to DLE]; theWelbio-Fonds National de la Recherche Scientifique, Belgium and Dutch Diabetes Fonds, Holland [2018.10.002 to DLE]; the Brussels CapitalRegion-Innoviris project Diatype [2017-PFS-24 to DLE, MC]; Fonds National de laRecherche Scientifique, Belgium [to MC]. This change does not affect the results, discussion and conclusions presented in the article. The published article has been updated.