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Low doses of anti-CD3, ciclosporin A and the vitamin D analogue, TX527, synergise to delay recurrence of autoimmune diabetes in an islet-transplanted NOD mouse model of diabetes.

par Baeke, F.;Van Belle, Tom L;Takiishi, Tatiana ;Ding, Lei;Korf, Hannelie;Laureys, Jos;Gysemans, C;Mathieu, Chantal
Référence Diabetologia, 55, 10, page (2723-2732)
Publication Publié, 2012-10

Article révisé par les pairs

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Titre:	Low doses of anti-CD3, ciclosporin A and the vitamin D analogue, TX527, synergise to delay recurrence of autoimmune diabetes in an islet-transplanted NOD mouse model of diabetes.
Auteur:	Baeke, F.; Van Belle, Tom L; Takiishi, Tatiana; Ding, Lei; Korf, Hannelie; Laureys, Jos; Gysemans, C; Mathieu, Chantal
Informations sur la publication:	Diabetologia, 55, 10, page (2723-2732)
Statut de publication:	Publié, 2012-10
Sujet CREF:	Diabétologie
	Immunologie
	Endocrinologie
	Biologie cellulaire
	Biologie
MeSH keywords:	Alkynes -- therapeutic use
	Animals
	Antibodies, Monoclonal -- immunology -- therapeutic use
	CD3 Complex -- immunology
	Cell Proliferation
	Cholecalciferol -- therapeutic use
	Cyclosporine -- therapeutic use
	Diabetes Mellitus, Type 1 -- immunology -- pathology -- prevention & control -- surgery
	Disease Models, Animal
	Dose-Response Relationship, Drug
	Drug Synergism
	Female
	Islets of Langerhans Transplantation -- immunology -- pathology
	Male
	Mice
	Mice, Inbred NOD
	Secondary Prevention
	T-Lymphocytes -- pathology
	Vitamin D -- analogs & derivatives
Langue:	Anglais
Identificateurs:	urn:issn:0012-186X
	info:doi/10.1007/s00125-012-2630-1
	info:pii/10.1007/s00125-012-2630-1
	info:pmid/22752077