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The prior infection with SARS-CoV-2 study (PICOV) in nursing home residents and staff - study protocol description and presentation of preliminary findings on symptoms.

par Goossens, Maria M.E.;Neven, Kristof KY;Pannus, Pieter;Barbezange, Cyril;Thomas, Isabelle ;Gucht, Steven Van;Dierick, Katelijne;Schmickler, Marie-Noëlle;Verbrugghe, Mathieu;Loon, Nele Van;Ariën, Kevin;Marchant, Arnaud ;Goriely, Stanislas ;Desombere, Isabelle
Référence Archives of public health, 79, 1, page (195)
Publication Publié, 2021-11-01

Article révisé par les pairs

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Résumé :

The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has presented itself as one of the most important health concerns of the 2020's, and hit the geriatric population the hardest. The presence of co-morbidities and immune ageing in the elderly lead to an increased susceptibility to COVID-19, as is the case for other influenza-like illnesses (ILI) or acute respiratory tract infections (ARI). However, little is known, about the impact of a previous or current infection on the other in terms of susceptibility, immune response, and clinical course. The aim of the "Prior Infection with SARS-COV-2" (PICOV) study is to compare the time to occurrence of an ILI or ARI between participants with a confirmed past SARS-CoV-2 infection (previously infected) and those without a confirmed past infection (naïve) in residents and staff members of nursing homes. This paper describes the study design and population characteristics at baseline.