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Preoperative ketorolac administration has no preemptive analgesic effect for minor orthopaedic surgery

par Vanlersberghe, Caroline;Lauwers, Marylin;Camu, Frédéric
Référence Acta anaesthesiologica Scandinavica, 40, 8 I, page (948-952)
Publication Publié, 1996

Article révisé par les pairs

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Résumé :

The utility of preoperative ketorolac administration to reduce the intensity and duration of postoperative pain was compared with placebo in a randomized double-blind design of 60 ASA 1-2 patients scheduled for minor orthopaedic surgery. No opioids nor local anaesthetic blocks were used during surgery. The patients received either 30 mg ketorolac IV before surgery followed by a placebo injection after surgery or the reverse. Postoperative pain intensity was assessed repeatedly for 6 h using a visual analogue scale. No differences in pain intensity were observed between the two groups except for the initial 15-min postoperative assesments in the ketorolac group. The time to first rescue morphine administration and the total morphine consumption during the 6-h observation period were similar. It is concluded that the preoperative administration of ketorolac did not provide a significant preemptive analgesic t with regard to postoperative pain relief and opioid dose-sparing effect.