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Relax, Keep Walking - A Practical Guide to Continuous Phylogeographic Inference with BEAST

par Dellicour, Simon ;Gill, Mandev M.S.;Faria, Nuno Rodrigues;Rambaut, Andrew;Pybus, Oliver George;Suchard, Marc M.A.;Lemey, Philippe
Référence Molecular biology and evolution, 38, 8, page (3486-3493)
Publication Publié, 2021-08

Article révisé par les pairs

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Résumé :

Spatially explicit phylogeographic analyses can be performed with an inference framework that employs relaxed random walks to reconstruct phylogenetic dispersal histories in continuous space. This core model was first implemented 10 years ago and has opened up new opportunities in the field of phylodynamics, allowing researchers to map and analyze the spatial dissemination of rapidly evolving pathogens. We here provide a detailed and step-by-step guide on how to set up, run, and interpret continuous phylogeographic analyses using the programs BEAUti, BEAST, Tracer, and TreeAnnotator.