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Influence of viscosity and surfactant on fissure penetration of dental fluoride gels in vitro

par Bottenberg, Peter ;Slop, D.;Remon, J.P.;De Muynck, C.;Coomans, D.
Référence International journal of pharmaceutics, 49, 2, page (147-156)
Publication Publié, 1989-01

Article révisé par les pairs

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Résumé :

In this in vitro study the influence of viscosity and surface tension of dental fluoride-containing gels, morphological characteristicsof human and artificial occlusal fissures and the penetration of these fluoride gels into fissures is demonstrated. Self-preparedhydroxyethylcellulose gels with viscosities ranging from 75 to 5800 mPas containing 1.23% NaF are used. Sodium laurylsulphate wasadded to one group. While viscosity plays a secondary role in the penetration of the gels, surface tension and fissure morphology arevery important. The shallow-wide type of fissure is filled by all of the gels. The deep-narrow type of fissure is penetrated only by gelscontaining sodium laurylsulphate.