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Synthesis of a new class of pyrrolo[3,4-h]quinazolines with antimitotic activity.

par Spanò, Virginia;Montalbano, Alessandra;Carbone, Anna;Parrino, Barbara;Diana, Patrizia;Cirrincione, Girolamo;Castagliuolo, Ignazio;Brun, Paola;Issinger, Olaf-Georg;Tisi, Silvia;Primac, Irina ;Vedaldi, Daniela;Salvador, Alessia;Barraja, Paola
Référence European journal of medicinal chemistry, 74, page (340-357)
Publication Publié, 2014-03

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Titre:	Synthesis of a new class of pyrrolo[3,4-h]quinazolines with antimitotic activity.
Auteur:	Spanò, Virginia; Montalbano, Alessandra; Carbone, Anna; Parrino, Barbara; Diana, Patrizia; Cirrincione, Girolamo; Castagliuolo, Ignazio; Brun, Paola; Issinger, Olaf-Georg; Tisi, Silvia; Primac, Irina; Vedaldi, Daniela; Salvador, Alessia; Barraja, Paola
Informations sur la publication:	European journal of medicinal chemistry, 74, page (340-357)
Statut de publication:	Publié, 2014-03
Sujet CREF:	Sciences bio-médicales et agricoles
Mots-clés:	Antimitotic activity
	Antiproliferative activity
	Pyrrolo[3,4-h]quinazolines
	Tubulin polymerization
	Vascular disrupting activity
MeSH keywords:	Cell Death -- drug effects
	Cell Line, Tumor
	Human Umbilical Vein Endothelial Cells
	Humans
	Lysosomes -- physiology
	Mitochondria -- physiology
	Mitosis -- drug effects
	Pyrroles -- chemistry
	Quinazolines -- chemical synthesis -- chemistry -- pharmacology
Langue:	Anglais
Identificateurs:	urn:issn:0223-5234
	info:doi/10.1016/j.ejmech.2013.10.014
	info:pii/S0223-5234(13)00655-7
	info:pmid/24486413