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Blocking lipid synthesis overcomes tumor regrowth and metastasis after antiangiogenic therapy withdrawal.

par Sounni, Nor Eddine;Cimino, Jonathan;Blacher, Silvia;Primac, Irina ;Truong, Alice;Mazzucchelli, Gabriel;Paye, Alexandra;Calligaris, David;Debois, Delphine;De Tullio, Pascal;Mari, Bernard;De Pauw, Edwin;Noël, Agnès
Référence Cell Metabolism, 20, 2, page (280-294)
Publication Publié, 2014-08

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Titre:	Blocking lipid synthesis overcomes tumor regrowth and metastasis after antiangiogenic therapy withdrawal.
Auteur:	Sounni, Nor Eddine; Cimino, Jonathan; Blacher, Silvia; Primac, Irina; Truong, Alice; Mazzucchelli, Gabriel; Paye, Alexandra; Calligaris, David; Debois, Delphine; De Tullio, Pascal; Mari, Bernard; De Pauw, Edwin; Noël, Agnès
Informations sur la publication:	Cell Metabolism, 20, 2, page (280-294)
Statut de publication:	Publié, 2014-08
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Angiogenesis Inhibitors -- therapeutic use
	Animals
	Cell Line, Tumor
	Disease Progression
	Fatty Acid Synthases -- antagonists & inhibitors -- genetics -- metabolism
	Homeodomain Proteins -- genetics -- metabolism
	Humans
	Indoles -- therapeutic use
	Lipids -- biosynthesis
	Metabolomics
	Mice
	Mice, Inbred C57BL
	Mice, Knockout
	Neoplasm Metastasis
	Neoplasms -- drug therapy -- metabolism -- pathology
	Neovascularization, Pathologic -- drug therapy -- metabolism
	Niacinamide -- analogs & derivatives -- therapeutic use
	Phenylurea Compounds -- therapeutic use
	Proteomics
	Pyrroles -- therapeutic use
	RNA Interference
	Sorafenib
	Sunitinib
	Transplantation, Heterologous
Langue:	Anglais
Identificateurs:	urn:issn:1550-4131
	info:doi/10.1016/j.cmet.2014.05.022
	info:pii/S1550-4131(14)00266-6
	info:pmid/25017943