par Merimi, Makram ;Lagneaux, Laurence ;Lombard, Catherine A;Moussa Agha, Douaa ;Bron, Dominique ;Lewalle, Philippe ;Meuleman, Nathalie ;Najimi, Mustapha;Sokal, Etienne M;Najar, Mehdi
Référence Inflammation research
Publication Publié, 2021-01
Référence Inflammation research
Publication Publié, 2021-01
Article révisé par les pairs
Résumé : | One of the main challenges in liver cell therapy is the replacement of damaged cells and the induction of a tolerogenic microenvironment to promote graft acceptance by the recipient. Adult-derived human liver stem/progenitor cells (ADHLSCs) are currently evaluated at the clinical levels as a promising pro-regenerative and immune-modulatory tool. The expression profile of several immunological molecules may influence the local immune-inflammatory response and, therefore, modulate the tissue healing process. To increase the quality and safety of ADHLSCs before transplantation requires an appropriate analysis and characterization of their pattern expression of immune-inflammatory-associated molecules. |