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Sodium-glucose cotransporter 2 inhibitors antagonize lipotoxicity in human myeloid angiogenic cells and ADP-dependent activation in human platelets: potential relevance to prevention of cardiovascular events.

par Spigoni, Valentina;Fantuzzi, Federica ;Carubbi, Cecilia;Pozzi, Giulia;Masselli, Elena;Gobbi, Giuliana;Solini, Anna;Bonadonna, Riccardo R.C.;Dei Cas, Alessandra
Référence Cardiovascular diabetology, 19, 1, page (46)
Publication Publié, 2020-04-07

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Titre:	Sodium-glucose cotransporter 2 inhibitors antagonize lipotoxicity in human myeloid angiogenic cells and ADP-dependent activation in human platelets: potential relevance to prevention of cardiovascular events.
Auteur:	Spigoni, Valentina; Fantuzzi, Federica; Carubbi, Cecilia; Pozzi, Giulia; Masselli, Elena; Gobbi, Giuliana; Solini, Anna; Bonadonna, Riccardo R.C.; Dei Cas, Alessandra
Informations sur la publication:	Cardiovascular diabetology, 19, 1, page (46)
Statut de publication:	Publié, 2020-04-07
Sujet CREF:	Sciences bio-médicales et agricoles
Mots-clés:	Atherosclerosis
	Myeloid angiogenic cells
	Platelets
	SGLT-2 inhibitors
	Sodium-proton exchanger
MeSH keywords:	Adenosine Diphosphate -- pharmacology
	Apoptosis -- drug effects
	Benzhydryl Compounds -- pharmacology
	Blood Platelets -- drug effects -- metabolism -- pathology
	Cells, Cultured
	Endothelial Progenitor Cells -- drug effects -- metabolism -- pathology
	Glucosides -- pharmacology
	Humans
	Inflammation Mediators -- metabolism
	Oxidative Stress -- drug effects
	Platelet Activation -- drug effects
	Signal Transduction
	Sodium-Glucose Transporter 2 -- metabolism
	Sodium-Glucose Transporter 2 Inhibitors -- pharmacology
	Sodium-Hydrogen Exchangers -- metabolism
	Stearic Acids -- toxicity
Langue:	Anglais
Identificateurs:	urn:issn:1475-2840
	info:doi/10.1186/s12933-020-01016-5
	info:pii/10.1186/s12933-020-01016-5
	info:pmid/32264868
	PMC7140327