par Bohlok, Ali 
;Vermeulen, Peter B.;Leduc, Sophia ;Latacz, Emily;Botzenhart, Lara Maria ;Richard, François;De Schepper, Maxim;Geukens, Tatjana;Lucidi, Valerio ;Ignatiadis, Michail ;Aftimos, Philippe ;Sotiriou, Christos ;Piccart-Gebhart, Martine ;Hendlisz, Alain ;Van Laere, Steven;Dirix, Luc Y;Noël, Jean Christophe ;Biganzoli, Elia;Larsimont, Denis ;Desmedt, Christine ;Donckier De Donceel, Vincent
Référence NPJ breast cancer, 6, 1, 64
Publication Publié, 2020-12
;Vermeulen, Peter B.;Leduc, Sophia ;Latacz, Emily;Botzenhart, Lara Maria ;Richard, François;De Schepper, Maxim;Geukens, Tatjana;Lucidi, Valerio ;Ignatiadis, Michail ;Aftimos, Philippe ;Sotiriou, Christos ;Piccart-Gebhart, Martine ;Hendlisz, Alain ;Van Laere, Steven;Dirix, Luc Y;Noël, Jean Christophe ;Biganzoli, Elia;Larsimont, Denis ;Desmedt, Christine ;Donckier De Donceel, Vincent Référence NPJ breast cancer, 6, 1, 64
Publication Publié, 2020-12
Article révisé par les pairs
| Résumé : | Currently, there are no markers to identify patients with liver-only or liver-dominant metastases that would benefit from hepatic surgery. Here we characterized histopathological growth patterns (HGPs) of liver metastases in a consecutive series of 36 breast cancer patients who underwent hepatic surgery. Survival analyses showed that the presence of a desmoplastic HGP in the liver metastases (a rim of fibrous tissue separating cancer cells from the liver parenchyma, present in 20 (56%) patients) is independently associated with favorable progression-free and overall survival when compared with the replacement HGP (cancer cells growing into the liver parenchyma, present in 16 (44%) patients). |
