par Hosseinzadeh, Medhi
Référence Control Applications for Biomedical Engineering Systems, Elsevier Inc., page (89-125)
Publication Publié, 2020-01
Partie d'ouvrage collectif
Résumé : During general anesthesia, anesthesiologists adjust the level of hypnosis based on dose regimes given by drug manufacturers and their own observation. Thus, their actions are comparable to those of a closed-loop control scheme. Although control technology has been applied to several medical applications where a human patient is in the loop, lack of knowledge about mechanisms of hypnosis and its large intrapatient and interpatient variability (model uncertainty), had prevented development of an automatic hypnotic drug delivery system. Recent advances in sensing devices along with robust control methods have generated new hopes of finally bridging the gap between manual and automated control of hypnosis. The aim of this chapter is collecting and systematizing in a common framework the numerous contributions dispersed regarding robust control of depth of hypnosis. More precisely, in this chapter, the most recent results are discussed and a perspective on some open research directions is provided.