Titre:
  • Hematopoiesis specific loss of Cdk2 and Cdk4 results in increased erythrocyte size and delayed platelet recovery following stress.
Auteur:Jayapal, Senthil Raja; Wang, Chelsia Qiuxia; Bisteau, Xavier; Caldez, Matias MJ; Lim, Shuhui; Tergaonkar, Vinay; Osato, Motomi; Kaldis, Philipp
Informations sur la publication:Haematologica, 100, 4, page (431-438)
Statut de publication:Publié, 2015-04
Sujet CREF:Sciences bio-médicales et agricoles
Biologie
Biologie moléculaire
Biologie cellulaire
MeSH keywords:Animals
Blood Platelets -- metabolism
Cell Size
Cyclin-Dependent Kinase 2 -- deficiency -- genetics
Cyclin-Dependent Kinase 4 -- deficiency -- genetics
Erythrocytes -- cytology
Female
Gene Deletion
Hematocrit
Hematopoiesis -- genetics
Hematopoietic Stem Cells -- metabolism
Immunophenotyping
Male
Mice
Mice, Knockout
Phenotype
Ploidies
Retinoblastoma Protein -- genetics
Stress, Physiological
Langue:Anglais
Identificateurs:urn:issn:0390-6078
info:doi/10.3324/haematol.2014.106468
info:pii/haematol.2014.106468
info:pmid/25616574
PMC4380715