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Contribution à l' étude de la physiologie et de la physiopathologie du sommeil chez l' individu normal et les patients souffrant de dépression majeure et d 'insomnie primaire

par Hein, Matthieu ;Lanquart, Jean Pol ;Loas, Gwenolé ;Hubain, Philippe ;Linkowski, Paul
Référence Revue médicale de Bruxelles, 41, 3, page (137-142)
Publication Publié, 2020-09-01

Article révisé par les pairs

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Résumé :

In this doctoral work, we have demonstrated that in chronic insomnia and subtypes of major depression with objective insomnia, the hyperarousal is a fundamental pathophysiological mechanism promoting the occurrence of cardio-metabollc complications and alterations of neurotransmission during sleep. In these particular subpopulatlons, It therefore seems essential to put in place appropriate therapeutic strategies to block the phenomenon of hyperarousal throughout the night in order to allow a better cardio-metabolic prevention and a better clinical evolution both symptomatically and cognitively.