Article révisé par les pairs
| Résumé : | In order to test the possibility for microsomes to multiply like viruses, microsomes of chick liver were inoculated on chorioallantoïc membranes. The glucose-6-phosphatase activity, an enzyme located in the liver microsomes, was determined in the treated membranes. The activity decreased during the first 24 h after inoculation. It reached, after 48 h, from two to six times the value attained after 24 h. A suspension of heated granules, or of heated Tétrahymèna géléii, though producing the same lesions of the membrane, did not increase the phosphatase activity of the microsome fraction after 48 h. The present results are compatible with the idea that liver microsomes multiply by autoduplication. |
