Résumé : A goal-oriented a-posteriori error estimator is developed for transient coupled Thermo-Hydro-Mechanical (THM) parametric problems solved with a reduced basis approximation. The estimator assesses the error in some specific Quantity of Interest (QoI). The goal-oriented error estimate is derived based on explicitly-computed weak residual of the primal problem and implicitly-computed adjoint solution associated with the QoI. The time-dependence of the coupled THM system poses an additional complexity as the auxiliary adjoint problem evolves backwards in time. The error estimator guides a greedy adaptive procedure that constructs progressively an optimal reduced basis by smartly selecting snapshot points over a given parametric training sample. The reduced basis obtained is used to drastically reduce the coupled system spatial degrees of freedom by several orders of magnitude. The computational gain obtained from the developed methodology is demonstrated through applications in 2D and 3D parametrized problems simulating the evolution of coupled THM processes in rock masses.