Hormonal circadian rhythms and sleep in aging

Copinschi, Georges; Caufriez, Anne

doi:doi/10.1016/B978-0-12-801238-3.65189-9

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Hormonal circadian rhythms and sleep in aging

par Copinschi, Georges

;Caufriez, Anne

Référence Encyclopedia of Endocrine Diseases, Elsevier, page (675-689)
Publication Publié, 2018-01

Partie d'ouvrage collectif

Résumé :

The 24-h temporal regulation of hormonal secretions results from the interaction of an endogenous circadian pacemaker and of sleep-wake homeostasis, a mechanism linking the timing and the intensity of sleep to the duration of prior wakefulness. A reduction in rhythm amplitude and an advance shifting constitute prominent age-related alterations of hormonal circadian rhythmicity. At the same time, the sleep-wake pattern undergoes major modifications, with a spectacular decrease in “restorative” sleep stage from early adulthood to mid-life, followed thereafter by sleep fragmentation and a decrease in total sleep time. Age-related sleep and endocrine-metabolic alterations frequently interact with each other.

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