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Effects of essential amino acids supplementation on muscle damage following a heavy-load eccentric training session

par Vieillevoye, Stéphanie ;Poortmans, Jacques ;Carpentier, Alain
Référence Science & sports, 35, 5, page (125-134)
Publication Publié, 2020-12-01

Article révisé par les pairs

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Résumé :

Aim. — Unaccustomed physical exercise, particularly repeated eccentric muscle contractions,induces muscle soreness and alterations on muscle cellular structure. An increase in myofibrillarprotein accretion can occur in the early post-exercise period and be potentiated by essentialamino acid ingestion. We hypothesized that essential amino acid supplementation could reducethe efflux of indirect markers of muscle damage and delay the onset of muscular soreness inthe week following a heavy-load eccentric training session.Methods. — Twenty-three randomly assigned young males performed a bench press exerciseunder eccentric condition. They were subdivided into a placebo group (n = 11) and an essential amino acids group (n = 12). The effect of the training session was assessed by analysingtwo indirect markers of muscle damage, namely plasma concentrations of creatine kinase andmyoglobin measured before, immediately after, and post-workout day 1, 2, 3, 4 and 7. Musclesoreness was evaluated by a visual analogy scale at the same time point as the markers ofmuscle damage.