par Vanherweghem, Jean-Louis 
;Schoutens, André ;Bergmann, Pierre ;D'haene, Michel ;Goldman, Michel ;Fuss, Michel ;Kinnaert, Paul
Référence Proceedings of the European Dialysis and Transplant Association, 21, page (431-434)
Publication Publié, 1984
;Schoutens, André ;Bergmann, Pierre ;D'haene, Michel ;Goldman, Michel ;Fuss, Michel ;Kinnaert, Paul Référence Proceedings of the European Dialysis and Transplant Association, 21, page (431-434)
Publication Publié, 1984
Article révisé par les pairs
| Résumé : | Fogelman's score (FS) was used to determine the usefulness of 99mTc pyrophosphate (Tc-PP) bone scintigraphy in the evaluation of dialysis osteodystrophy. FS correlated well with bone 47Ca accretion rate. It remained stable after six months in patients treated with 1 alpha (OH)D3 and increased significantly in a randomised group of untreated patients. It decreased after two years of 1 alpha (OH)D3 therapy while serum calcium increased and iPTH and alkaline phosphatases decreased. Patients with low FS, treated by 1 alpha (OH)D3, rapidly developed hypercalcaemia. In cases of spontaneous hypercalcaemia, parathyroidectomy did not normalise serum calcium in patients with low FS despite a significant decrease in serum iPTH. Lower FS were associated with a higher increase in serum aluminium after desferrioxamine (DFO) administration and in two cases of proven aluminium osteomalacia, DFO therapy was followed by a dramatic increase in FS. |
