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The effects of some inhibitors of RNA synthesis and proteolysis on morphogenesis in Acetabularia mediterranea

par Brachet, Jean
Référence Biochemie und Physiologie der Pflanzen, 168, 5-6, page (493-510)
Publication Publié, 1975

Article révisé par les pairs

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Résumé :

The effects of a number of inhibitors of RNA synthesis and proteolysis on morphogenesis in Acetabularia have been studied. While camptothecin had no effect, cordycepin acted like actinomycin D: it did not inhibit cap formation in anucleate halves, but stopped growth in nucleate ones. Two inhibitors of trypsin-like protease, TLCK and TAME, arrested morphogenesis and growth in both kinds of fragments; inhibition was reversible in nucleate halves; in anucleate halves, it was irreversible after TLCK, partially reversible after TAME treatment. No binding sites for Con A coud be detected with fluorescent lectin. Two organomercurials (PCMB, PCMBS) inhibited strongly growth and morphogenesis in both kinds of fragment; reversibility is much better in nucleate halves than in anucleate ones. The significance of these results is discussed.