par Mastracci, Teresa TL;Turatsinze, Jean Valéry ;Book, Benita BK;Restrepo, Ivan IA;Pugia, Michael MJ;Wiebke, Eric EA;Pescovitz, Mark D;Eizirik, Decio L. ;Mirmira, Raghavendra R.G.
Référence Diabetes, obesity and metabolism, 20, 8, page (1859-1867)
Publication Publié, 2018
Référence Diabetes, obesity and metabolism, 20, 8, page (1859-1867)
Publication Publié, 2018
Article révisé par les pairs
Résumé : | Our current understanding of the pathogenesis of type 1 diabetes (T1D) arose, in large part, from studies using the non-obese diabetic (NOD) mouse model. In the present study, we chose a human-focused method to investigate T1D disease mechanisms and potential targets for therapeutic intervention by directly analysing human donor pancreatic islets from individuals with T1D. |